| 38776 | Spekku-man | ZX-Spectrum 48K | English |
| 4747 | Spi-Droid | ZX-Spectrum 48K | English |
| 16832 | Spider | ZX-Spectrum 16K | English |
| 19974 | Spider | ZX-Spectrum 16K | English |
| 25953 | Spiders | ZX-Spectrum 48K | English |
| 25447 | Spiders Revenge | ZX-Spectrum 48K | English |
| 25471 | Spidoid | ZX-Spectrum 48K | English |
| 28352 | Splat! | SAM Coupé | English |
| 4767 | Splat! | ZX-Spectrum 48K | English |
| 20552 | Spooks Attack | ZX-Spectrum 48K | English |
| 4776 | Spookyman | ZX-Spectrum 16K | English |
| 37846 | Spuckman | ZX-Spectrum 48K | English |
| 29331 | Star-Way | ZX81 16K | English |
| 4873 | Starquake | ZX-Spectrum 48K | English |
| 30336 | Stela II | ZX-Spectrum 48K | Multi-language: English, Spanish |
| 26087 | Stellar Run | ZX-Spectrum 16K | English |
| 27879 | Sterospace Oddysey | ZX-Spectrum 48K | English |
| 18380 | Stomper | ZX-Spectrum 16K | English |
| 4918 | Storm | ZX-Spectrum 48K | English |
| 4963 | Strontium Dog: The Killing | ZX-Spectrum 48K | English |