| 6937 | The Sealed City | ZX-Spectrum 48K | English |
| 36498 | The Seance | ZX-Spectrum 48K | English |
| 6940 | The Search for the Wonderful Whotsit | ZX-Spectrum 128K | English |
| 22438 | The Secret City of Kokos Khan | ZX-Spectrum 48K | English |
| 5960 | The Secret of Arendarvon Castle | ZX-Spectrum 48K | Dutch |
| 6949 | The Secret of Little Hodcome | ZX-Spectrum 48K | English |
| 10920 | The Sefton Manor Assignment | ZX-Spectrum 48K | English |
| 15138 | The Semi-Detached at the End of the Street | ZX-Spectrum 48K | English |
| 6955 | The Serf's Tale | ZX-Spectrum 48K | English |
| 19506 | The Seven Cities of Cibola | ZX-Spectrum 16K | English |
| 42556 | The Sirens of Space | ZX-Spectrum 48K | English |
| 36090 | The Six Foot Tall Man Eating Chicken (ZxZvm) | ZX-Spectrum 128 +3 | - |
| 6984 | The Slaughter Caves | ZX-Spectrum 48K | English |
| 6991 | The Snow Queen | ZX-Spectrum 48K | English |
| 7005 | The Song of Taliesin | ZX-Spectrum 48K | English |
| 10931 | The Spectre of Booballyhoo | ZX-Spectrum 48K | English |
| 7019 | The Spectre of Castle Coris | ZX-Spectrum 48K/128K | English |
| 16695 | The Spectre of Larry Horsfield | ZX-Spectrum 48K | English |
| 10233 | The Spiro Legacy | ZX-Spectrum 128K | English |
| 43745 | The St. Petersburg Ikon | ZX-Spectrum 48K | English |