| 34502 | E.T. MC | ZX81 16K | English |
| 42968 | E.T.: The Extra Terrestrial | SAM Coupé | English |
| 31475 | ERASE | ZX-Spectrum 48K | English |
| 36743 | ESPECTRON | ZX-Spectrum 16K | Portuguese |
| 36741 | ESPECTROids | ZX-Spectrum 16K | Portuguese |
| 42502 | EXO-TICAL | ZX-Spectrum 48K/128K | English |
| 40143 | Early Bird | ZX-Spectrum 48K | English |
| 43818 | Earth Defence | ZX-Spectrum 16K/48K | English |
| 30744 | Earth Girls Make Tasty Snacks | ZX-Spectrum 48K | English |
| 1569 | EastEnders | ZX-Spectrum 48K | English |
| 17802 | Easyfrog | ZX-Spectrum 16K | English |
| 31041 | Eat Shit! | ZX-Spectrum 16K | English |
| 44536 | Ecclesia | ZX-Spectrum 128K | English |
| 44426 | Echa un culín | ZX-Spectrum 16K | English |
| 9698 | Eddy Electric | ZX-Spectrum 48K | English |
| 9699 | Efenders | ZX-Spectrum 48K | English |
| 17708 | Egbert | ZX-Spectrum 48K | English |
| 28846 | Egg | ZX81 16K | English |
| 24595 | Egg | ZX-Spectrum 48K | Russian |
| 1577 | Egg Farm | ZX-Spectrum 16K | English |