| 38635 | Searcher | ZX-Spectrum 48K | English |
| 19537 | Searle | ZX-Spectrum 48K | English |
| 6941 | Seas of Blood | ZX-Spectrum 48K | English |
| 10918 | Seaside Sorcery | ZX-Spectrum 48K | English |
| 21062 | Season of the Sakura | ZX-Spectrum 48K | English |
| 25931 | Season's Greeting | ZX-Spectrum 48K | English |
| 35433 | Second Life | ZX-Spectrum 48K | Czech |
| 25611 | Second Opinion | ZX-Spectrum 48K | English |
| 23182 | Second Opinion | ZX-Spectrum 48K | English |
| 22243 | Secopy | ZX-Spectrum 48K | English |
| 20487 | Secret Mission | ZX-Spectrum 48K | English |
| 6947 | Secret Mission | ZX-Spectrum 48K | English |
| 6948 | Secret Mission - 007 James Bond | ZX-Spectrum 48K | Czech |
| 23118 | Secret Mission Radio | ZX-Spectrum 48K | English |
| 10919 | Secret Valley | ZX-Spectrum 48K | English |
| 43394 | Secrets: The Castle of Doom | ZX-Spectrum 48K | English |
| 4391 | Sector 90 | ZX-Spectrum 48K | English |
| 22552 | Sector Search | ZX-Spectrum 48K | English |
| 39100 | Sector Strike! | ZX-Spectrum 48K | English |
| 34378 | Sector and Sector Invasion | ZX-Spectrum 48K | English |