| 32414 | Slacker X - A Scatological Breakthrough in Adventure Gaming (ZxZvm) | ZX-Spectrum 128 +3 | English |
| 8683 | SlowDOS | ZX-Spectrum 128 +3 | English |
| 15050 | Slowglass | ZX-Spectrum 128 +3 | Spanish |
| 32415 | So Far - An Interactive Catharsis (ZxZvm) | ZX-Spectrum 128 +3 | English |
| 32416 | SoftPorn Adventure - An Interactive Classic (ZxZvm) | ZX-Spectrum 128 +3 | English |
| 22242 | Softrom! | ZX-Spectrum 128 +3 | English |
| 44430 | Solo Dos Deseos | ZX-Spectrum 128 +3 | Spanish |
| 32417 | Sorcerer - Interlogic Fantasy (ZxZvm) | ZX-Spectrum 128 +3 | English |
| 36091 | Space Station (ZxZvm) | ZX-Spectrum 128 +3 | - |
| 32418 | Space Under the Window (ZxZvm) | ZX-Spectrum 128 +3 | English |
| 37675 | SpecQuest | ZX-Spectrum 128 +3 | English |
| 22563 | Spectop | ZX-Spectrum 128 +3 | English |
| 25193 | Spectrum +3 Spectacular | ZX-Spectrum 128 +3 | English |
| 9420 | Spectrum CP/M Plus | ZX-Spectrum 128 +3 | English |
| 14024 | Spectrum CP/M Plus + Mallard BASIC | ZX-Spectrum 128 +3 | English |
| 32419 | Spellbreaker - An Interactive Fantasy (ZxZvm) | ZX-Spectrum 128 +3 | English |
| 32420 | SpiritWrak - An Interactive Fantasy Adventure (ZxZvm) | ZX-Spectrum 128 +3 | English |
| 12477 | Sportacular Disk 1 | ZX-Spectrum 128 +3 | English |
| 42400 | Starbyte + Rex Hard | ZX-Spectrum 128 +3 | Spanish |
| 32421 | Starcross - Interlogic Science Fiction (ZxZvm) | ZX-Spectrum 128 +3 | English |