| 35812 | Russian Railway Magnate | ZX-Spectrum 48K | Multi-language: English, Russian |
| 4303 | Sagenhafte Schatz des Minotaurus | ZX-Spectrum 48K | English |
| 6921 | Samurai Warrior | ZX-Spectrum 16K | English |
| 4330 | Santa Paravia en Fiumaccio | ZX-Spectrum 48K | Dutch |
| 38516 | Seldon's Game | ZX-Spectrum 16K | English |
| 14795 | Share Bizz | ZX-Spectrum 48K | English |
| 20714 | Shares | ZX-Spectrum 48K | English |
| 6971 | Ship of the Line | ZX-Spectrum 16K/48K | English |
| 26804 | Shopkeeper | ZX-Spectrum 48K | English |
| 44496 | Sib City | ZX-Spectrum 48K | Multi-language: English, Russian |
| 27193 | Simulacion de Empresas | ZX-Spectrum 48K | Spanish |
| 30594 | Sir Clive Sinclair - Entrepreneur Extrordinaire | ZX-Spectrum 48K | English |
| 19674 | Sir Francis Drake | ZX-Spectrum 48K | English |
| 31081 | Slap Me Forum Troll | ZX-Spectrum 48K | English |
| 20733 | Slavemaker | ZX-Spectrum 128K | - |
| 29289 | Smaug's Lair | ZX81 16K | English |
| 4581 | Smuggler | ZX-Spectrum 48K | English |
| 4620 | Software House | ZX-Spectrum 48K | English |
| 4621 | Software Star | ZX-Spectrum 48K | English |
| 7004 | Sonar Salvage | ZX-Spectrum 48K | English |