| 23027 | Skyscraper of Doom | ZX-Spectrum 48K | English |
| 18862 | Skyway | ZX-Spectrum 48K | English |
| 4567 | Sleepwalker | ZX-Spectrum 48K | English |
| 17200 | Sliders | ZX-Spectrum 128K | Russian |
| 9418 | Slightly Magic | ZX-Spectrum 48K/128K | English |
| 24427 | Slightly Spooky | ZX-Spectrum 48K/128K | English |
| 13051 | Smagly | ZX-Spectrum 128K | Russian |
| 13052 | Smagly 2 | ZX-Spectrum 128K | Russian |
| 4597 | Snodgits | ZX-Spectrum 48K | English |
| 35172 | Sochi Nights | ZX-Spectrum 48K/128K | English |
| 12083 | Solar Jetman | ZX-Spectrum 128K | English |
| 4631 | Soldier of Fortune | ZX-Spectrum 48K | English |
| 4000264 | Sonâmbulo | Timex Tx2068 | Portuguese |
| 4647 | Sooty & Sweep | ZX-Spectrum 48K | English |
| 4650 | Sorcery | ZX-Spectrum 48K | English |
| 37694 | Sorcery Island | ZX-Spectrum 48K | Multi-language: English, Spanish |
| 34671 | Sorcery+ | ZX-Spectrum 48K | English |
| 43980 | SpAIder's Game | ZX-Spectrum 128K | Multi-language: English, Spanish |
| 4657 | Space 7 | ZX-Spectrum 48K | English |
| 4687 | Space Worm | ZX-Spectrum 48K | English |