| 4687 | Space Worm | ZX-Spectrum 48K | English |
| 4703 | Specimen | ZX-Spectrum 48K | English |
| 4704 | Specimen II: The Apple Quest | ZX-Spectrum 48K | English |
| 9337 | Spellbound Dizzy | ZX-Spectrum 48K/128K | English |
| 26203 | Spike | ZX-Spectrum 48K | Spanish |
| 9421 | Spike in Transylvania | ZX-Spectrum 48K/128K | English |
| 20551 | Spirit Level | ZX-Spectrum 48K | English |
| 4760 | Spirits | ZX-Spectrum 48K | Spanish |
| 35441 | Stalker | ZX-Spectrum 48K | Czech |
| 4889 | Star Wars Droids | ZX-Spectrum 48K/128K | English |
| 10242 | Starburst | ZX-Spectrum 48K | English |
| 23618 | Starfire | ZX-Spectrum 48K | English |
| 41868 | Starman | ZX-Spectrum Next | English |
| 9424 | Steg | ZX-Spectrum 48K/128K | English |
| 12126 | Stellar Holocaust | ZX-Spectrum 48K | English |
| 36621 | Steps | ZX81 16K | English |
| 4919 | Stormbringer | ZX-Spectrum 48K/128K | English |
| 4922 | Stormlord | ZX-Spectrum 48K/128K | English |
| 4925 | Stormlord II: Deliverance | ZX-Spectrum 48K/128K | English |
| 4926 | Strangeloop | ZX-Spectrum 48K | English |